Entendendo o Endocanabinóide: a tal Maconha Interna!

Ciência, Discovery Hemp, Featured, Medicinal

hempadao 9 junho, 2019

Você sabia que todo ser humano, usuário ou não de cannabis, tem um sistema endocanabinóide?

por Paulo Cesar

A maconha é uma planta milenar. A proibição é recente, mas fez com que os estudos a respeito da planta demorassem a acontecer. Por exemplo, os primeiros endocanabinóides só foram descobertos e isolados do tecido humano em 1992. Foram eles: a anandamida e o 2-araquidonoil glicerol. A descoberta, publicada na Revista Science, por William Devane, comprova que o nosso organismo produz uma substância análoga aos canabinóides presentes na maconha.

O termo “ananda”, oriundo do sânscrito, significa “felicidade serena” ou “bem-aventurança”. Descoberto quatro anos antes, em 88, a anandamida reage com seu receptor canabinóide, chamado CB1. Já o receptor CB2 foi encontrado no ano seguinte e, junto ao anterior, compõem os principais endocanabinóides alvos de estudo.

Ou seja, embora a cannabis seja uma fonte de mais de 60 canabinoides (incluindo o THC e o CBD), a verdade é que o corpo humano também produz vários canabinoides. Basicamente, eles formam o que é conhecido como Sistema Endocanabinóide. Estes canabinoides endógenos estão presentes em todos os seres humanos e regulam funções diversas de nosso organismo.

Ao que sabe hoje em dia, podemos dizer que o sistema endocanabinóide é constituído pelo seguinte conjunto: receptores canabinóides, os endocanabinóides e as enzimas que catalisam sua degradação e biossíntese.

O que ele faz?

O sistema endocanabinóide encontra-se amplamente distribuído no sistema nervoso e em menor quantidade em tecidos periféricos. Esse sistema faz a comunicação entre o cérebro e muitas funções fisiológicas do corpo, isso explica o fato dele ser constante alvo de estudos para fins terapêuticos. Uma de suas principais funções é manter a homeostase, que consiste na capacidade do nosso organismo em manter a estabilidade do organismo, tal como temperatura corporal, níveis de água e minerais, regulação da glicose no sangue, dentre muitos outros.

Os endocanabinóides são produzidos em doses baixas por enzimas de nosso corpo. A partir de administrações terapêuticas de canabinóides, é possível ter benefícios sobre diversas doenças. A ativação do receptor CB1 é alvo de diversos estudos, pois ele tem: envolvimento na diminuição da sensibilidade aos estímulos dolorosos, efeitos ansiolíticos, atividade antitumoral, neuroproteção diante de situações de trauma e falta de oxigênio para feto durante a gravidez, modulação da ingestão de alimentos.

Já a ativação do receptor CB2 tem propriedade de reduzir danos provocados por doenças auto-imune. No organismo, os endocanabinóides estão envolvidos na regulação da ingestão alimentar, controle do nível energético das células e até no controle de humor. A seguir, pode-se observar o efeito na cannabis em outros tecidos periféricos que apresentam o sistema endocanabinóide:

“O sistema endocanabinóide reduz a sensação de dor, controla o movimento, a memória, o sono, o apetite e protege”, resumiu o pesquisador Di Marzo.

Fonte: AQUI



71 respostas para “Entendendo o Endocanabinóide: a tal Maconha Interna!”

  1. While most coaches provide water for the team, you should always bring some along.

  2. Avatar Joker Slot disse:

    Serious work and persistence is required to make real strides when it comes to your game.

  3. Avatar SAGAME disse:

    This intimidates the viewers sense of comfort and ease of reading.

  4. By following this pregame ritual, you will decrease your chances of sustaining a connective tissue injury.

  5. Check out tips that blogging professionals use, and apply them in your own blogs so that your profits will be increased.

  6. Majority of the traffic that your site will receive is going to come from search engines such as Yahoo, Google or Bing.

  7. It truly is mostly extremely difficult to encounter well-updated men or women on this theme, and yet you appear like you realize what exactly you’re indicating! Regards

  8. Faytech North America is a touch screen Manufacturer of both monitors and pcs. They specialize in the design, development, manufacturing and marketing of Capacitive touch screen, Resistive touch screen, Industrial touch screen, IP65 touch screen, touchscreen monitors and integrated touchscreen PCs. Contact them at http://www.faytech.us, 121 Varick Street, New York, NY 10013, +1 646 205 3214.

  9. Avatar tizenx disse:

    This is a very good tip especially to those new to the blogosphere. Short but very accurate information… Many thanks for sharing this one. A must read article!

  10. Avatar khdima disse:

    I love it when individuals come together and share ideas. Great site, stick with it.

  11. MetroClick specializes in building completely interactive products like Photo Booth for rental or sale, Touch Screen Kiosks, Large Touch Screen Displays , Monitors, Digital Signages and experiences. With our own hardware production facility and in-house software development teams, we are able to achieve the highest level of customization and versatility for Photo Booths, Touch Screen Kiosks, Touch Screen Monitors and Digital Signage. Visit MetroClick in NYC at http://www.metroclick.com/ or , 121 Varick St, New York, NY 10013, +1 646-843-0888.

  12. Avatar Best CBD Oil disse:

    I was extremely pleased to discover this site. I want to to thank you for your time due to this fantastic read!! I definitely savored every bit of it and I have you bookmarked to see new things in your blog.

  13. It’s nearly extremely difficult to come across well-updated readers on this subject, still you seem like you understand those things you’re writing on! Gratitude

  14. Sapid Agency is a Search Engine Optimization company in New York City that provides SEO Services. Their proprietary SEO strategies help struggling websites and aspiring business owners to rank their websites higher in multiple search engines like Google , Yahoo and Bing. They provide local and gmb map ranking for businesses in NYC and many other local areas. Find more at https://www.sapidagency.com/ @ 145 E 57TH NEW YORK, NY 10022, USA, +1 971 341 5608 USA

  15. Hello! I could have sworn I’ve been to this site before but after going through many of the posts I realized it’s new to me. Nonetheless, I’m definitely delighted I came across it and I’ll be book-marking it and checking back regularly!

  16. After I originally commented I seem to have clicked on the -Notify me when new comments are added- checkbox and now every time a comment is added I receive 4 emails with the same comment. There has to be a means you are able to remove me from that service? Thanks a lot.

  17. Avatar pmp exam disse:

    Can I just say what a comfort to discover someone who genuinely understands what they’re talking about online. You definitely understand how to bring a problem to light and make it important. A lot more people should read this and understand this side of your story. I was surprised you’re not more popular given that you surely have the gift.

  18. An impressive share! I’ve just forwarded this onto a friend who has been doing a little research on this. And he in fact bought me lunch simply because I stumbled upon it for him… lol. So let me reword this…. Thank YOU for the meal!! But yeah, thanks for spending time to discuss this subject here on your site.

  19. I’m pretty pleased to find this web site. I want to to thank you for ones time due to this wonderful read!! I definitely appreciated every part of it and i also have you bookmarked to check out new information on your website.

  20. Avatar view disse:

    Good day here, just got familiar with your web page through yahoo, and realized that it is really helpful. I will appreciate should you decide persist such.

  21. I blog quite often and I really thank you for your information. This great article has truly
    peaked my interest. I’m going to take a note of your site and keep checking for new
    information about once a week. I opted in for your RSS
    feed as well.

  22. Thanks for helping out, good info. “The surest way to be deceived is to think oneself cleverer than the others.” by La Rochefoucauld.

  23. This is a good tip particularly to those fresh to the blogosphere. Short but very accurate information… Many thanks for sharing this one. A must read article.

  24. You’re so interesting! I don’t suppose I’ve read through something like that before. So wonderful to find someone with some original thoughts on this issue. Really.. many thanks for starting this up. This web site is something that is needed on the web, someone with some originality.

  25. I truly enjoy studying on this web site, it has got wonderful articles. “A short saying oft contains much wisdom.” by Sophocles.

  26. Avatar cogethers disse:

    Aw, this was a really good post. Finding the time and actual effort to generate a great article… but what can I say… I put things off a whole lot and never seem to get anything done.

  27. Your area is valueble for me. Thanks !?

  28. It’s actually nearly not possible to find well-informed women and men on this content, nevertheless you come across as like you fully understand what exactly you’re indicating! Thanks A Lot

  29. You made some really good points there. I checked on the net for more information about the issue and found most people will go along with your views on this website.

  30. I wanted to thank you for this great read!! I definitely loved every bit of it. I have you book-marked to check out new stuff you post…

  31. Some genuinely select blog posts on this website , saved to favorites .

  32. Avatar trucks disse:

    Nice post. I learn something totally new and challenging on sites I stumbleupon on a daily basis. It will always be helpful to read content from other writers and practice a little something from their web sites.

  33. I view something truly special in this internet site.

  34. Avatar ufa888a disse:

    Great article. I’m dealing with a few of these issues as well..

  35. Hi, Neat post. There’s an issue with your site in web explorer, might check this… IE still is the market chief and a huge component of other folks will pass over your great writing due to this problem.

  36. Hey I know this is off topic but I was wondering if
    you knew of any widgets I could add to my blog that automatically tweet my newest
    twitter updates. I’ve been looking for a plug-in like this for quite some time and was hoping maybe you would
    have some experience with something like this.
    Please let me know if you run into anything. I truly enjoy reading your blog and I look forward to your new updates.

  37. Avatar Bridal Shower disse:

    Good site you have here.. It’s hard to find high-quality writing like yours nowadays. I honestly appreciate individuals like you! Take care!!

  38. Avatar sellefied disse:

    I could not refrain from commenting. Perfectly written!

  39. Avatar fires account disse:

    I’m pretty pleased to find this great site. I need to to thank you for your time for this wonderful read!! I definitely enjoyed every part of it and I have you saved as a favorite to check out new stuff in your website.

  40. It’s nearly impossible to find knowledgeable people on this subject, but you seem like you know what you’re talking about! Thanks

  41. Avatar those g disse:

    I used to be suggested this blog by means of my cousin. I’m not certain whether this submit is
    written via him as nobody else realize such targeted approximately my problem.
    You are wonderful! Thank you!

  42. Sapid Agency is a Search Engine Optimization company in New York City that provides SEO Services. Their proprietary SEO strategies help struggling websites and aspiring business owners to rank their websites higher in multiple search engines like Google , Yahoo and Bing. They provide local and gmb map ranking for businesses in NYC and many other local areas. Find more at https://www.sapidagency.com/ @ 145 E 57TH NEW YORK, NY 10022, USA, +1 971 341 5608 USA

  43. I needed to thank you for this wonderful read!! I definitely loved every little bit of it. I’ve got you book-marked to look at new stuff you post…

  44. Avatar would g disse:

    I’m impressed, I must say. Seldom do I encounter a blog that’s equally educative
    and entertaining, and without a doubt, you’ve hit the
    nail on the head. The problem is something which too few folks are speaking intelligently about.
    I’m very happy I stumbled across this in my hunt for something relating to this.

  45. I couldn’t refrain from commenting. Very well written!

  46. FreeSpinner is made to help you getting the results you deserve.

  47. Having read this I believed it was rather informative. I appreciate you taking the time and effort to put this content together. I once again find myself personally spending way too much time both reading and posting comments. But so what, it was still worth it.

  48. Avatar my concrete disse:

    I like reading a post that will make men and women think. Also, many thanks for allowing me to comment.

  49. Avatar wealth disse:

    Hi, I do think this is a great site. I stumbledupon it 😉 I’m going to come back once again since i have book-marked it. Money and freedom is the greatest way to change, may you be rich and continue to help other people.

  50. When I initially commented I seem to have clicked the -Notify me when new comments are added- checkbox and from now on every time a comment is added I receive four emails with the exact same comment. Perhaps there is a way you are able to remove me from that service? Appreciate it.

  51. After looking over a handful of the blog posts on your web page, I honestly like your technique of writing a blog. I saved as a favorite it to my bookmark website list and will be checking back soon. Take a look at my website as well and let me know how you feel.

  52. MetroClick specializes in building completely interactive products like Photo Booth for rental or sale, Touch Screen Kiosks, Large Touch Screen Displays , Monitors, Digital Signages and experiences. With our own hardware production facility and in-house software development teams, we are able to achieve the highest level of customization and versatility for Photo Booths, Touch Screen Kiosks, Touch Screen Monitors and Digital Signage. Visit MetroClick in NYC at http://www.metroclick.com/ or , 121 Varick St, New York, NY 10013, +1 646-843-0888.

  53. Avatar hiphop beats disse:

    I blog quite often and I really appreciate your content. This article has really peaked my interest. I am going to take a note of your website and keep checking for new information about once a week. I subscribed to your Feed as well.

  54. The very next time I read a blog, Hopefully it doesn’t fail me just as much as this one. After all, Yes, it was my choice to read, however I genuinely thought you would have something interesting to say. All I hear is a bunch of whining about something you can fix if you were not too busy searching for attention.

  55. May I simply just say what a comfort to find a person that actually knows what they are discussing on the internet. You definitely understand how to bring an issue to light and make it important. More people should read this and understand this side of your story. I was surprised you aren’t more popular since you most certainly have the gift.

  56. I could not refrain from commenting. Exceptionally well written!

  57. Having read this I believed it was extremely informative. I appreciate you spending some time and effort to put this article together. I once again find myself personally spending a significant amount of time both reading and posting comments. But so what, it was still worth it.

  58. An impressive share! I have just forwarded this onto a friend who was conducting a little homework on this. And he in fact ordered me lunch simply because I found it for him… lol. So allow me to reword this…. Thank YOU for the meal!! But yeah, thanx for spending some time to discuss this subject here on your web site.

  59. I’m impressed, I have to admit. Seldom do I encounter a blog that’s both equally educative and amusing, and without a doubt, you’ve hit the nail on the head. The issue is something that too few folks are speaking intelligently about. I’m very happy that I found this in my hunt for something regarding this.

  60. Right here is the right webpage for anyone who would like to find out about this topic. You know so much its almost hard to argue with you (not that I really will need to…HaHa). You certainly put a brand new spin on a subject that has been written about for decades. Wonderful stuff, just great.

  61. Do you believe past life hypnosis? Do you think is reincarnation real?

  62. This is a topic that is near to my heart… Take care! Where can I find the contact details for questions?

  63. I blog frequently and I truly appreciate your content. The article has truly peaked my interest. I will bookmark your blog and keep checking for new information about once a week. I subscribed to your Feed as well.

  64. Avatar fashion urban disse:

    Oh my goodness! Amazing article dude! Thank you, However I am encountering troubles with your RSS. I don’t understand the reason why I cannot subscribe to it. Is there anyone else getting the same RSS problems? Anyone who knows the solution can you kindly respond? Thanks.

  65. Is your webdesigner looking for a job. I think your site is great.

  66. Avatar Jenise Garbe disse:

    I was just looking for this information for some time. After six hours of continuous Googleing, finally I got it in your website. I wonder what’s the lack of Google strategy that do not rank this type of informative sites in top of the list. Generally the top sites are full of garbage.

  67. I simply want to say I’m beginner to blogs and really liked this page. Probably I’m want to bookmark your website . You definitely have superb articles and reviews. Appreciate it for sharing with us your website.

Deixe uma resposta

O seu endereço de e-mail não será publicado. Campos obrigatórios são marcados com *




[pro_ad_display_adzone id=17608]
[pro_ad_display_adzone id=17609]